Our science
The science of enough.
How a yeast peptide fits into your body's own fullness signaling, what is known about it, and what isn't.
The signal
GLP-1, in plain English.
GLP-1 is a hormone your gut makes when food arrives. It travels to the brain and the pancreas with a simple message: a meal has landed.
Among other things, GLP-1 helps you feel full and slows how quickly your stomach empties, so a meal tends to carry you further. It's one of several signals your body uses to manage appetite, and it rises and falls through the day.
Where food noise comes in
Food noise is the running commentary about food that carries on after you've eaten: the snack you keep thinking about, the evening visit to the fridge. Appetite isn't only willpower. It runs on signals between your gut and your brain.
Where Signal comes in
Signal is made to support your body's own GLP-1 signaling, not to replace it.* It doesn't contain GLP-1 or any prescription medicine. It's a dietary supplement.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Food noise
The voice that keeps bringing up the snack drawer.
Food noise is the running commentary about food that carries on after you've eaten. Appetite isn't only willpower. It runs on signals between your gut and your brain.
GLP-1 is one of the messages your gut sends when a meal arrives. Among other things, it tells your brain you've had enough. Signal is made to support that message, not to replace it.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
An illustration of the idea, not a measurement. Everyone responds differently.
How it works
Two tablets. One signal.
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1
Take two tablets
Once a day, with water, at a time you'll remember. You can go up to three.
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2
The peptide meets your gut
Signal's yeast peptide is made to support the gut cells that release GLP-1 when you eat.*
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3
Fullness arrives sooner
GLP-1 tells your brain a meal has landed and slows how fast your stomach empties, so a meal can carry you further.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The ingredient
One ingredient, made with yeast.
Signal is 560 mg of a peptide made with Saccharomyces cerevisiae, the same yeast species used for bread and beer, in every two-tablet serving.
There's no blend and no hidden amount. The only other things in the tablet are what holds it together and coats it: cellulose, modified cellulose, titanium dioxide and citric acid ester.
The whole label
One ingredient. The amount is on the front.
Signal is 560 mg of a peptide made with Saccharomyces cerevisiae, the yeast species behind bread and beer, pressed into a tablet with plant cellulose. That's the whole formula, and everything else in the tablet is listed on the panel.
Not in the bottle
- Caffeine
- Stimulants
- Proprietary blends
- Hidden amounts
Supplement Facts
Serving Size 2 Tablets
Servings Per Container 30
† Daily Value not established.
Other ingredients: Vegetable tablet (cellulose, modified cellulose), tablet coating (titanium dioxide, citric acid ester).
Directions: Take 2 tablets daily with water. You may take up to 3.
What we know, and what we don't
We haven't run a trial on Signal. We'll say so until we have.
Research on yeast peptides and appetite is early, and we haven't run a clinical trial on Signal itself. That's why you won't see a pounds-lost number from us, and why the guarantee gives you 60 days to judge it for yourself.
The evidence pageWhat is a yeast peptide?
A peptide is a short chain of amino acids. Signal's is made with Saccharomyces cerevisiae, a yeast species people have used in food for thousands of years.
Does Signal contain GLP-1?
No. It contains no GLP-1 hormone and no prescription GLP-1 medicine. It's made to support your body's own GLP-1 signaling.*
How is it different from prescription GLP-1 medicines?
Those are drugs, prescribed and dosed by a clinician. Signal is a dietary supplement. They are not interchangeable, and Signal won't do what a prescription does.
How is it different from herbal fat burners?
Most lean on caffeine, green tea extract or capsaicin. Signal has no stimulants at all.
Has Signal been clinically tested?
Not by us. We haven't run a clinical trial on Signal. When we have evidence of our own, we'll publish it in full on the evidence page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The 60-day trial
Give it 60 days. Keep it or send it back.
Take Signal every day for two months. If it hasn't earned a place in your routine, send back what's left, even an empty bottle, for a full refund of the product price.
From $148 a bottle · free US shipping