How it works

Two tablets. One signal.

How to take Signal, what the first 60 days look like, and how to choose the right supply.

Shop Signal

How it works

Two tablets. One signal.

  1. 1

    Take two tablets

    Once a day, with water, at a time you'll remember. You can go up to three.

  2. 2

    The peptide meets your gut

    Signal's yeast peptide is made to support the gut cells that release GLP-1 when you eat.*

  3. 3

    Fullness arrives sooner

    GLP-1 tells your brain a meal has landed and slows how fast your stomach empties, so a meal can carry you further.*

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Woman taking a white oblong Signal tablet

Your first 60 days

What to expect, honestly.

  1. Day 1

    Start the habit

    Two tablets with water, at the same time each day. Breakfast is easiest to remember.

  2. Weeks 1-2

    Watch the gaps

    Pay attention to the time between meals. That's where appetite support shows up first, if it's going to for you.*

  3. Weeks 3-6

    Stay consistent

    Daily use matters more than timing. Meals with protein in them give it the best chance.*

  4. Day 60

    Decide

    If Signal hasn't earned a place in your day, send back what's left, even an empty bottle, for a full refund of the product price.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

60-second self-check

How loud is your food noise?

Four quick questions. At the end you'll get a suggestion for how long to give Signal.

A self-check, not a medical assessment. Nothing you tap here is saved or sent anywhere.

Question 1 of 4 How often do you think about food when you aren't hungry?

Made for you

Find your fit.

  1. 01The GLP-1 curious

    Interested in GLP-1. Not ready for a prescription or a needle.

    Sound familiar
    You want something simple you can take with breakfast and forget about.
    Where Signal fits
    A daily tablet made to support your body's own GLP-1 signaling.*
    This sounds like me

  2. 02The grazer

    Meals are fine. It's everything in between.

    Sound familiar
    The snack drawer, the evening fridge visit, the second helping you didn't really want.
    Where Signal fits
    Made to help quiet cravings between meals.*
    This sounds like me

  3. 03The long game

    You want steady, not another quick fix.

    Sound familiar
    You've tried the stimulant route and the crash that came with it.
    Where Signal fits
    No stimulants, made to support fullness over months, not days.*
    This sounds like me

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Oratide Signal: a matte espresso-brown bottle with SIGNAL printed vertically. 60 tablets, 560 mg yeast peptide per serving.

GLP-1 support · oral peptide tablets

Signal

Two tablets a day of a 560 mg yeast peptide, made to support the signal your gut sends when you've had enough.*

Skip, change or cancel any time.

Choose your supply
  • 60-day money-back guarantee, even on an empty bottle
  • Free US shipping · most orders leave Florida the same business day
  • 1 ingredient · 60 tablets per bottle · no stimulants
See everything about Signal

Side by side

The same 560 mg. A fairer deal.

The best-known GLP-1 supplement uses the same amount of yeast peptide per serving. Here's what's different.

Compared Oratide Signal Leading GLP-1 supplement
Yeast peptide per serving 560 mg 560 mg
One bottle, 30 days $89 $148
Lowest price per day $2.30 $4.19
Money back if it isn't for you 60 days, even on an empty bottle No returns or refunds
Free US shipping Yes Yes

† Figures as published on the leading brand's own product page and refund policy, checked 4 October 2026.