GLP-1 support · oral peptide tablets
Signal
Turn down the food noise.*
- 560 mg yeast peptide per 2-tablet serving
- No stimulants no caffeine, no jitters
- 60-day guarantee even on an empty bottle
- From $4.93 a day on the 3-bottle supply
Signal is one ingredient: a yeast peptide made to support the signal your gut sends when you've had enough.* Two tablets a day, made to help you:
- Quiet food noise and cravings between meals*
- Feel full sooner after you eat*
- Support healthy weight management with diet and exercise*
Choose your supply
Skip, change or cancel any time.
The guarantee runs 60 days, so two bottles cover the whole window.
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60-day money-back guarantee. Send back what's left, even an empty bottle, within 60 days of your billing date for a full refund of the product price.
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Free US shipping. Standard shipping is free on this order. Most orders leave Florida the same business day.
- No prescription
- No needles
- No stimulants
- One ingredient
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
How to take it
Two tablets once a day with water. You can go up to three a day. Breakfast is the easiest time to remember. One bottle lasts 30 days at two a day.
Are there side effects?
Signal is made from yeast, and yeast products are generally well tolerated. Don't take it if you're allergic or sensitive to yeast. If anything happens after taking it, stop and call (929) 525-4811, the number on the label.
Ingredients
Yeast peptide (Saccharomyces cerevisiae S288C), 560 mg per 2 tablets.
Other ingredients: cellulose, modified cellulose, tablet coating (titanium dioxide, citric acid ester).
How is it different from fat burners?
Most metabolism supplements lean on caffeine, green tea extract or capsaicin for a short buzz. Signal has no stimulants at all. It's a peptide made to support your body's own fullness signaling.*
Is Signal a drug?
No. It's a dietary supplement. It contains no prescription GLP-1 medicine and doesn't replace one. If you take one, talk to your prescriber before adding anything.
Your first 60 days
What to expect, honestly.
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Day 1
Start the habit
Two tablets with water, at the same time each day. Breakfast is easiest to remember.
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Weeks 1-2
Watch the gaps
Pay attention to the time between meals. That's where appetite support shows up first, if it's going to for you.*
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Weeks 3-6
Stay consistent
Daily use matters more than timing. Meals with protein in them give it the best chance.*
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Day 60
Decide
If Signal hasn't earned a place in your day, send back what's left, even an empty bottle, for a full refund of the product price.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Food noise
The voice that keeps bringing up the snack drawer.
Food noise is the running commentary about food that carries on after you've eaten. Appetite isn't only willpower. It runs on signals between your gut and your brain.
GLP-1 is one of the messages your gut sends when a meal arrives. Among other things, it tells your brain you've had enough. Signal is made to support that message, not to replace it.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
An illustration of the idea, not a measurement. Everyone responds differently.
How it works
Two tablets. One signal.
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1
Take two tablets
Once a day, with water, at a time you'll remember. You can go up to three.
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2
The peptide meets your gut
Signal's yeast peptide is made to support the gut cells that release GLP-1 when you eat.*
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3
Fullness arrives sooner
GLP-1 tells your brain a meal has landed and slows how fast your stomach empties, so a meal can carry you further.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The whole label
One ingredient. The amount is on the front.
Signal is 560 mg of a peptide made with Saccharomyces cerevisiae, the yeast species behind bread and beer, pressed into a tablet with plant cellulose. That's the whole formula, and everything else in the tablet is listed on the panel.
Not in the bottle
- Caffeine
- Stimulants
- Proprietary blends
- Hidden amounts
Supplement Facts
Serving Size 2 Tablets
Servings Per Container 30
† Daily Value not established.
Other ingredients: Vegetable tablet (cellulose, modified cellulose), tablet coating (titanium dioxide, citric acid ester).
Directions: Take 2 tablets daily with water. You may take up to 3.
Side by side
The same 560 mg. A fairer deal.
The best-known GLP-1 supplement uses the same amount of yeast peptide per serving. Here's what's different.
| Compared | Oratide Signal | Leading GLP-1 supplement |
|---|---|---|
| Yeast peptide per serving | 560 mg | 560 mg |
| One bottle, 30 days | $89 | $148 |
| Lowest price per day | $2.30 | $4.19 |
| Money back if it isn't for you | 60 days, even on an empty bottle | No returns or refunds |
| Free US shipping | Yes | Yes |
† Figures as published on the leading brand's own product page and refund policy, checked 4 October 2026.
What we know, and what we don't
We haven't run a trial on Signal. Here's what you get instead.
Research on yeast peptides and appetite is early, and we haven't run a clinical trial on Signal itself. So you won't find a pounds-lost number on this page. You get the whole label, a fair price, and 60 days to decide, with your money back if it isn't for you.
The evidence pageHow is Signal different from prescription GLP-1 medicines?
Prescription GLP-1 medicines are drugs, prescribed and dosed by a clinician. Signal is a yeast peptide made to support your body's own GLP-1 signaling.* They are not interchangeable, and Signal won't do what a prescription does. If you take one, don't stop or change it without talking to your prescriber.
Can I take it with a GLP-1 prescription or diabetes medication?
Ask your doctor first. That goes for any supplement if you take medication or are managing a health condition.
When will I notice something?
Everyone is different, and we won't promise a day. Give it consistent daily use. That's why the guarantee runs for 60 days.
Who shouldn't take it?
Anyone under 18, and anyone pregnant or nursing. If you take medication or have a medical condition, check with your doctor before starting.
What if it isn't for me?
Email support@oratide.com within 60 days of your billing date for a return number, then send back what's left, even an empty bottle. You'll get a full refund of the product price. Shipping isn't refunded.
Where do you ship, and how fast?
Anywhere in the United States, from St Marks, Florida. Standard shipping is free on orders of $70 or more and takes 5-7 business days. Express is $15 and takes 2-3 business days.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The 60-day trial
Give it 60 days. Keep it or send it back.
Take Signal every day for two months. If it hasn't earned a place in your routine, send back what's left, even an empty bottle, for a full refund of the product price.
From $148 a bottle · free US shipping